Murillo is a town and municipality in the Tolima department of Colombia. The municipality borders Villahermosa to the north, Santa Isabel to the south, Líbano to the east, and the departments of Caldas and Risaralda to the west. Murillo is the highest town in the Tolima department. The western border of the municipality includes the peaks of Nevado del Ruiz, Nevado El Cisne, and Nevado Santa Isabel.